Two novel Pd thiosemicarbazone complexes as efficient and selective antitumoral drugs
نویسندگان
چکیده
Two Palladium complexes are presented as a promising alternative to platinum drugs disadvantages, controlling the speciation and limiting toxicity. Their interaction vs. biological targets their efficiency demonstrated, being more specific than benchmark cisplatin drug.
منابع مشابه
Stable gold(III) complexes with thiosemicarbazone derivatives.
Novel thiosemicarbazonato complexes of gold(III) have been prepared from reactions of [Au(damp-C1,N)Cl2(damp- = 2-(N,N-dimethylaminomethyl)phenyl) or [NBu4][AuCl4] with 2-pyridineformamide thiosemicarbazones (HL). The thiosemicarbazones deprotonate and coordinate as mononegative, tridentate NNS ligands to gold to give [Au(Hdamp-C1)(L)]Cl2 or [AuCl(L)]Cl complexes. The organometallic damp- ligan...
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ژورنال
عنوان ژورنال: Inorganic chemistry frontiers
سال: 2023
ISSN: ['2052-1553', '2052-1545']
DOI: https://doi.org/10.1039/d2qi02424a